Most joint pain, including neck and back pain, is caused by damaged, unhealed ligaments and tendons. If other abnormalities are present- . disk problems, cartilage problems, bone spurs, etc. , pain may still be arising from damaged, unhealed ligaments and tendons. Symptomatic connective tissue damage is often impossible to detect on imaging studies, but easy to detect on physical examination. Prolotherapy is the only therapy which successfully treats the underlying cause of most joint pain.

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